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Rowan Chapman, Colin Farlow, and Matt Kovac
Graphic depiction of robot hand editing DNA

The AI Effect: How a Hot Computing Tool Is Tying ‘Bio’ and ‘Tech’ Closer Than Ever

“In protein design, until the last couple of years, successes were rare,” said Fraser, a professor of bioengineering and therapeutic sciences in UCSF’s School of Pharmacy. “(AI has) just been a sea change. Stuff works now.” Those successes are elevating a new generation of AI-focused drug-development companies in the Bay Area, including Profluent Bio, a 20-person Berkeley startup founded by the leaders of the Salesforce project. In the wake created by ChatGPT and a wealth of biological data, those companies may be key to AI’s evolving ability to fix human ills. Read post
Sophia Lugo

Startup Launches With ‘RNA Sensor’ Technology From Stanford and MIT To Better Control mRNA Therapies

“We want to turn off an RNA transcript and prevent it from being expressed by default,” CSO Eerik Kaseniit, a former graduate student who worked on the technology in Gao’s lab, told Endpoints News in an interview. Radar’s scientists do that by adding a stop codon — three genetic letters that are the molecular equivalent of a red light — in front of the mRNA therapy, which prevents cells from reading the message. Read post
Illustration of hands exchanging money for lightbulb

Jim Collins’ Latest Venture Raises $13.4M To Programme Logic-Gated mRNA Therapies

Radar Therapeutics thinks it can push the technology to the next level – and into more diseases – with safety switches that boost cell specificity, safety, and accessibility. The biotech, co-founded by MIT professor and synthetic biology pioneer Jim Collins, launched Thursday with a $13.4-million seed round led by NfX Bio and boasting Eli Lilly as one of its investors. Read post
Illustration of person climbing ladder to reach into bush shaped like double helix

Radar Therapeutics Raises $13 Million to Design Therapies Using RNA Sensors

Radar Therapeutics emerged from stealth this week with an announcement that it had raised $13.4 million in an oversubscribed seed financing round led by NfX Bio. Eli Lilly & Co, Biovision, and KdT Ventures also joined the round, with participation from PearVC, BEVC, and other investors. They will use the funds to advance various internal programs, expand their team, and pursue partnership opportunities. Read post
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