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NY Times photographer Rachel Bujalski takes a photo of the Profluent team at BBH

Generative A.I. Arrives in the Gene Editing World of CRISPR

Much as ChatGPT learns to generate language by analyzing Wikipedia articles, books and chat logs, Profluent’s technology creates new gene editors after analyzing enormous amounts of biological data, including microscopic mechanisms that scientists already use to edit human DNA. Read post
Venkat Reddy, Greg Timblin, Ingrid Caton & David Moffat

Tenant Spotlight on Inapill: A Novel Approach to Interrupting Inflammation

“We hope this new oral therapeutic targeting proinflammatory immunometabolism will have ‘pipeline-in-a-pill’ potential,” says CEO and co-founder Greg Timblin. “Once it garners FDA approval in one inflammatory indication, it could be used in the clinic as a treatment across multiple inflammatory diseases. Perhaps it could even provide benefit to patients with more complex diseases where excessive inflammation is thought to be a driving factor, such as cardiometabolic and neurodegenerative diseases.” Read post
The East Bay Innovation award with Bakar Labs skylight in background

Bakar Labs Wins East Bay Innovation Award

The Innovation Award recognizes the real contribution Bakar Labs makes to the regional economy by supporting entrepreneurs building new companies, hiring skilled workers, bringing in investment, expanding their operations, and forging partnerships as they develop cures and solutions for the most urgent challenges that face us in human health. Since the incubator’s launch in November 2021, the 38 companies that we’ve hosted have raised more than $380 million and created more than 300 jobs. Read post
Screenshot of the Profluent homepage. "Decoding the language of life with AI"

Profluent Secures $35M in Additional Funding and Key Industry Experts to Scale Foundational AI Models for Biomedicine and Tackle First Vertical in Gene Editing

“Our research at the forefront of AI has enabled Profluent to create large language models that begin to learn the blueprint of nature,” said Ali Madani, Profluent co-founder and Chief Executive Officer. “We are moving biology from being constrained by what can be discovered in nature to being able to design precisely according to our needs via AI. The science is real and the time is now to proactively create breakthrough medicines that can transform society.” Read post
Bakar Labs in numbers
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The members of Allopartis in the QB3 Garage@UCSF incubator